From April 2024 to March 2025, the CDC reported 43,000 synthetic opioid deaths, most of which are from fentanyl, down from nearly 70,000 in the previous similar period. A person taking prescribed fentanyl can experience dependence, meaning they have withdrawal symptoms when they stop taking the drug. A person exhibiting the symptoms of overdose should get immediate medical attention. With an overdose of fentanyl, the brain experiences hypoxia.
How Easy Is It To Buy Fentanyl Online? Quite Easy, According To A Senate Report
In addition to receiving treatment for a substance use disorder, people who use illegal drugs can help prevent overdoses by using fentanyl test strips. These are low-cost paper strips that can detect fentanyl in all kinds and forms of substances. Fentanyl should only be prescribed by doctors who are experienced in treating pain in cancer patients.
Enhancing Healthcare Team Outcomes
Often drugs ordered from rogue websites come from foreign countries. It is a felony to import drugs into the United States and ship to a non-DEA registrant. The program not only educates parents and students but also school officials including administrators and teachers. FOX26 News confirmed with Fresno Unified School District beginning this year all middle and high schools will carry Narcan.

Any drug in any form (powder, pill) you get from a dealer, friend or an online source could have fentanyl in it. You can’t smell or taste fentanyl and fake pills made from fentanyl can look like real pills from a pharmacy. There’s no way to know if -or how much- fentanyl may be in them. Naloxone can reverse a fentanyl overdose, although in some cases it may take more doses because fentanyl is so potent. You should also call 911, just like for any medical emergency, so extra help is on the way. Because fentanyl can be created in a lab, it is much easier to produce and is, therefore, a cheaper alternative to less-potent opioids.

The Opioid Crisis: An Overview
- Others might freeze patches and then place frozen pieces under the tongue.
- There have been situations where people thought they were buying natural products, including weight-loss supplements, cannabis and anti-anxiety medications, and instead got fentanyl-laced drugs.
- Users and family members should have immediate access to naloxone (Narcan), an opioid agonist medication that rapidly reverses opioid overdose.
- Selling or giving away this medication may cause severe harm or death to others and is against the law.
- Fentanyl may cause serious harm or death if used accidentally by a child or by an adult who has not been prescribed the medication.
- Your doctor may need to adjust the dose of your other pain medication(s) to better control your pain.
It’s hard to predict the amount of fentanyl that could kill someone. As little as 2 milligrams may be lethal depending on how big your body is, what your tolerance for opioids is, and your past usage of fentanyl. After a fentanyl treatment, you may have side effects that hinder your thinking and reactions or cause dizziness or drowsiness.
NIH-funded Intervention Did Not Impact Opioid-related Overdose Death Rates Over Evaluation Period
Once you’ve been taking fentanyl for a while, your body gets used to it and stopping can be very hard. It can be hard to function without the drug in your system. Most people need help from a health professional or program to successfully quit. The U.S. Drug Enforcement Administration estimates more than 258,000 people died from fentanyl overdose between 2013 and 2021. Fentanyl acts like many other opioids such as morphine and heroin.

This combination can result in an individual consuming a much stronger substance than they are used to, resulting in overdose and possibly death. The DEA has found an average of 2.4 milligrams of fentanyl in the pills they test (DEA, 2024). Typically, a fentanyl overdose manifests as an extrapolation of its pharmacological side effects. Although the clinical scenarios may vary among patients, one of the main concerns is the level of expression of OIRD. In such cases, oxygen administration and respiratory assistance are a priority.
How To Reduce The Risk Of A Fentanyl Overdose
- You can’t smell or taste fentanyl and fake pills made from fentanyl can look like real pills from a pharmacy.
- An individual’s tolerance to fentanyl will impact the amount required to cause a fatal overdose.
- Many individuals consume fentanyl without knowledge while others use it intentionally because of its potency.
- Implications for overdose prevention and initiating treatment with medications for opioid use disorder are described.
- This causes feelings of well-being (euphoria) and relaxation and relieves pain.
Lastly, fentanyl use can extend to the treatment of epilepsy. That is, in combination with certain neuroleptic medications as part of therapeutic neuroleptanalgesia. Prescription fentanyl is FDA -approved to treat severe pain related to surgery or complex pain conditions. Over the past decade, fentanyl that is made and distributed illegally has become increasingly common in the illegal drug supply and has contributed to a surge in drug overdose deaths.
Why Is It So Dangerous?
These strips can be a useful harm reduction tool for people who drugs. Fentanyl test strips may not be able to detect all forms of illicit fentanyl and they cannot tell you how much fentanyl may be present. There can also be false positives (showing that fentanyl is present when it really isn’t). False positives are common when you test methamphetamine. The process of testing methamphetamine is different than testing opioids and uses more water.
Naloxone acts quickly to reverse the effects of an opioid overdose, but opioids last much longer than naloxone. Additional doses of naloxone are therefore sometimes necessary. People who receive naloxone still require an emergency medical evaluation, as overdose symptoms can return. If someone who has overdosed does not have a pulse, start CPR. Once the heart and brain have gone without oxygen for a while, naloxone will not work.

Watch a video on How to use fentanyl test strips from Prevent Overdose-Rhode Island. Learn more about law enforcement and overdose response here. There is no way to know how much fentanyl is in something based on look, smell, or taste. Any opioid pill not from a pharmacy is highly likely to be fake and contain fentanyl. The biggest risk factor is that people are often exposed unintentionally and don’t know to take the proper precautions to use this drug safely.
Illegal fentanyl is potent and deadly, and other drugs are often laced with it. An injection of naloxone can reverse the effects of the drug if given soon enough. A Narcan nasal spray is available over-the-counter and anyone can administer it.

Street names for fentanyl include Apache, China Girl, Goodfellas, Great Bear, and Tango & Cash. Fentanyl is an opioid pain reliever for use in medical treatment. Although healthcare professionals consider fentanyl safe and effective when a person uses it in a monitored medical setting, the drug carries a high potential for misuse, also known as abuse. Medications are the standard treatment for fentanyl addiction.32,33 Several medications have been approved by the U.S. Food and Drug Administration (FDA) for the treatment of opioid use disorder.
These sounded like sophisticated operations, offering discounts on bulk purchases and even trying to upsell the investigators to carfentanil, an even more powerful opioid. A lot of experts would say that tackling demand and making treatment more accessible should be the top priority. Still, this new Senate report reveals in stunning detail just how easy it is to order some of the most potent opioids available from the other side of the world.